Bottom Line:

Primal Mind Fuel by Primal Harvest features a premium blend of B vitamins and nootropics. Expertly formulated, it combines CogniPlex™ B vitamins (with vitamins B6, B12, and B1) with a NeuroSmart™ Blend that features rhodiola, Bacopa monnieri, l-tyrosine, theobromine, huperzine A, and D-glucuronolactone. 

This nootropic formula delivers premium ingredients in a convenient once-daily serving. As all high-quality supplements should be, Primal Mind Fuel is third-party lab tested and made in the USA with globally sourced ingredients in a GMP-certified facility. The product offers great value for money and the brand has a convenient Subscribe & Save program which means you can order this formula through their convenient and hassle-free subscription service. By signing up for a subscription you get 20% off all products plus free shipping. ​

To top it off, Primal Harvest has excellent customer service scores and a 90-day money-back guarantee. 

PROS

CONS

Bottom Line:

Alpha Brain by Onnit is a nootropic formulated with vitamin B6 as well as Onnit’s own Onnit Flow Blend, Onnit Focus Blend, and Onnit Fuel Blend. 

The formula comes in vegetarian capsules with a serving size of 2 capsules per day. The capsules are free of gluten and dairy and are third-party tested. The product contains a good range of ingredients in the formula, however, the price may be considered high since it only contains 15 servings per container.

PROS

CONS

Bottom Line:

Dynamic Brain by Stonehenge consists of a wide variety of ingredients, including amino acids, adaptogens, vitamins, and minerals. It contains 60 capsules, or a one-month supply, taken as a 2-capsule serving. It features some common go-to nootropic ingredients such as huperzine A and Bacopa monnieri and is third-party tested. It comes in a veggie capsule, but those with specific dietary needs should note that the product does contain fish and soy. 

PROS

CONS

Bottom Line:

Mind Lab Pro contains 11 nootropics including organic mushrooms and L-theanine. It features a variety of B vitamins and plant-based extracts and is both vegan-friendly and GMP-certified. However, the 2-4 capsule serving size might be inconvenient to take for some people. When purchased directly from the website, a one-month supply will set you back $69.00 which places this formula at the higher end of the price range in comparison to the other products included on this page. 

PROS

CONS

Bottom Line:

This brain supplement by FF contains a variety of vitamins and minerals such as vitamins A, B6, C, D, and E, zinc, iron, magnesium, and calcium. It features a variety of B vitamins and plant-based extracts and is both vegan-friendly and GMP-certified. However, the 2-4 capsule serving size might be inconvenient to take for some people. When purchased directly from the website, a one-month supply will set you back $69.00 which places this formula at the higher end of the price range in comparison to the other products included on this page. 

PROS

CONS

1. Primal Mind Fuel

by Primal Harvest

Rating A+

Our rating:

  • CogniPlex B vitamins
  • NeuroSmart nootropic blend
  • 1 capsule per day
  • 90-day money-back guarantee
  • Certified safety and purity testing 
  • Made in the USA with globally sourced ingredients
  • Only available online
  • Due to high demand, sometimes runs out of stock

2. Alpha Brain

by Onnit

Rating: B+

Our rating:

  • Includes B vitamins, l-tyrosine, l-theanine, and extracts
  • Third-party tested
  • 90-day money-back guarantee
  • 2-capsule serving size
  • 15 servings per container

3. Dynamic Brain

by Stonehenge

Rating B

Our rating:

  • Includes B vitamins and Bacopa monnieri
  • Third-party tested
  • 90-day money-back guarantee
  • Contains fish and soy
  • 2-capsule serving size

4. Mind Lab Pro

by Bloom Nutrition

Note C+

Our rating:

  • With B vitamins, l-tyrosine, and Bacopa monnieri
  • Includes mushroom
  • Third-party tested
  • 2 to 4-capsule serving size
  • Price
  • 30-day money-back guarantee

5. Brain Supplement

by FF

Note C

Our rating:

  • Includes a blend with Bacopa monnieri, huperzine A, and more
  • Vitamins and minerals
  • Third-party lab tested
  • Contains fish
  • 4-tablet serving size
  • 7-day return policy

Our Choice 2025

Based on 3739 Reviews of Primal Harvest 

Primal Mind Fuel

by Primal Harvest

  • CogniPlex™ B Vitamins
  • NeuroSmart™ Nootropic Blend
  • 1 Capsule Per Day
  • Made in our GMP-certified facility in the US
  • Free Shipping on Orders Over $75

Top 5 Nootropic Supplements of 2025

How we rated the Top 5 Nutritional Supplements

Each of our reviews is based on a factual analysis and comparison. We examine the ingredients, dosages and manufacturing processes to understand the quality of the product. In addition, we evaluate customer reviews, value for money and customer service to protect our readers from negative buying experiences. Although we may receive compensation for these reviews, we strive to provide objective comparisons based on facts.

EFFECTIVENESS 

INGREDIENTS

PRICE-PERFORMANCE 

CUSTOMER SERVICE 

Top Cognitive Supplements 2025

Citations

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Wellness Reviews provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

To see a list of our other references, please click here. 

Written by:

Angela Schulz

  • Expert tested

Published:

Potential Benefits of Cognitive Supplements*

Whether they're looking to support energy, stress, mental agility, or just their general cognitive well-being, some people choose to turn to high-quality cognitive support supplements thanks to the convenience they offer.*

It’s always important to consult with your personal physician before starting a new supplement routine.

Top Nootropic Ingredients in Supplements

There are certain nootropic ingredients that are popular in these types of cognitive support supplements. The ones to look for include:

Many of us experience times when our concentration, stress resistance, or mental performance could use a little extra support. It’s no wonder that cognitive supplements (also known as nootropics) have become hugely popular in the last few years. 

Many factors can cause a lag in cognitive performance, from daily stress, age, and lifestyle habits to dehydration and poor nutrition. 

Choosing a nootropic can be tricky, especially when there are so many choices out there. Read on to find out more about key ingredients, what to look for, and what to avoid, plus discover our top picks for the best nootropic supplements of 2024. 

What Are Nootropic Stacks?

Because of their complex nature, cognitive supplements are usually sold separately. However, it is possible to conveniently combine nootropic ingredients into a single formula in what is known as a “nootropic stack.”

A nootropic stack is a blend of several ingredients that work together in a complimentary way to support cognitive performance.*

What To Try To Avoid In Your Cognitive Support Supplement*

How Might Some Nootropics on the Market Not Meet Your Needs?

Unfortunately, some generic cognitive support supplements may not satisfy your needs or expectations.

Here are some factors you may want to try to avoid when choosing your cognitive support supplement:

  • Unclear Labels:  A quality nootropic supplement should clearly list exactly what’s included in the formula. It’s generally best to avoid products lacking transparency that don’t list all of the specific ingredients included in the formula’s cognitive blend.
  • Missing Safety Testing & Certifications: Choose a cognitive support supplement that has been independently third-party lab tested and manufactured in a GMP facility. These precautions will guarantee that the product is top quality and free from unwanted extras, such as contaminants, traces of heavy metals, or pesticides. *
  • False or Misleading Claims: Beware of any cognitive supplements that claim their product treats or cures any specific health issues or ailments, or promises miraculous results. Always speak to your doctor before starting a new supplement routine.*
  • Suspiciously Cheap Products: When it comes to your cognitive health, this is definitely not an area to test out suspiciously cheap products. There are plentiful options to choose from that are high value and still affordable. In this case, you do get what you pay for!
  • Apoaequorin (Jellyfish Protein): Among some of the many trendy memory boosters, Apoaequorin is a protein made by certain luminescent jellyfish that is found in some nootropic or cognitive support supplements.

What to Look For In A Cognitive Support Supplement*

Top Cognitive Support Supplements 2025

Key Ingredients

Ingredients To Avoid

Important Criteria

Primal Mind Fuel by Primal Harvest

Alpha Brain by Onnit

Dynamic Brain by Stonehenge

Mind Lab Pro by Mind Lab Pro

Brain Supplement by  FF

No Apoaequorin

90-Day Money-Back Guarantee

Third-Party Tested

Subscribe & Save Program

Rhodiola Rosea

Caffeine

L-Tyrosine

Huperzine A

B Vitamins

Bacopa Monnieri

*We try to update product information as often as we can. Please visit product websites for more information.

Discover our picks for the top nootropic supplements to support focus, energy levels, and performance.

*Individual results may vary

  • Rhodiola Rosea: Historically used as a remedy for centuries in Russia, Europe, and Asia, rhodiola is an adaptogen that may help support stress, mood, motivation, and fatigue.*
  • Caffeine: One of the most popular nootropic ingredients, caffeine creates an energizing effect (which is why many choose to start the day with a cup of Joe).  Caffeine may help support energy, focus, attention, mood, and athletic performance.*
  • L-Tyrosine: L-Tyrosine is an amino acid used by the brain for a number of functions. This amino acid has the potential to support mental performance during high-stress situations and fatigue, as well as to support mood, concentration, and motivation.*
  • Vitamin B: B vitamins, including B1, B6, B9, and B12, are considered important for maintaining brain health and energy (amongst other things). They may also help support mental clarity, energy production, and focus.*
  • Bacopa Monnieri: Bacopa monnieri is an antioxidant-rich herb that has been traditionally used for centuries in Traditional Chinese health practices and Ayurveda to support memory, stress, and potentially support learning.*

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*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. 

Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Top5 Wellness has with our picks.

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