Best Muscle Building & Test Support Supplements in 2025

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Written by:

Matthew Acciari

  • Expert tested
  • Evidenzbasiert

It's quite common for men to see a noticeable drop in testosterone levels starting age 40

Low test levels can be a catalyst for a number of embarassing issues including hair loss, muscle loss and worst of all, decline in performance in the bedroom. Many men seek natural ways to supporting their testosterone levels such as supplements or food. But what many people are unaware of are the nasty side effects of proprietary blends and questionable ingredients and dosages.

At Wellness Reviews, we have reviewed some of the most popular muscle building supplements on the market and shared them in this guide. Discover what we learned and which 5 made our list.

Published:

Popular Supplements For Men

These are the some of popular ingredients found in a number of in men’s health supplements:

  • KOREAN GINSENG ROOT: Health and wellness enthusiasts may already be familiar with American ginseng root, which is often used to support a healthy immune system. Korean red ginseng is slightly different and although has also been used in TCM to maintain immune and heart health and boost energy (like American ginseng), it is also used to support stress and male vitality. This multi-tasking root has shown promising results in recent studies, which suggest that there is a link between ginseng supplementation and drive. [9]
  • BORON: Supports testosterone impacting the sex hormone-binding globulin (SHBG), a protein that binds to testosterone and makes it inactive. When SHBG levels are high, less free testosterone is available for the body to use. By inhibiting SHBG, boron can help the increase in levels of active testosterone, supporting muscle growth, energy, and overall hormonal balance. Additionally, boron helps regulate estrogen levels and reduce inflammation, further promoting optimal testosterone function. [14]
  • TRIBULUS TERRESTRIS: Tribulus terrestris, also known as gokshura, is a small leafy plant used traditionally in Ayurveda and TCM to enhance drive and maintain a healthy urinary tract. Studies have suggested that men with lower drive found tribulus terrestris beneficial for their sexual health. Additionally, this extract also contains antioxidants called polyphenols which may have multiple wellness benefits due to their ability to neutralize free radicals and support against oxidative stress. [3, 4] 
  • FENUGREEK: You may have heard of this herb, commonly used as a spice in Indian cuisine. It has been used in CTM for its potential wellness benefits. Studies suggest it may help support normal testosterone levels in men which may help support a healthy drive and muscles. [13]
  • MACA ROOT: This root has been used for centuries in Peru as it contains bioactive compounds that are believed to have a number of wellness benefits. Not only do some studies suggest that it may be helpful for low desire, but it also shows promise in having a positive effect on mood and energy levels. [10] 
  • VITAMIN D: Also called the “sunshine vitamin”, vitamin D is a fat-soluble vitamin that is important for many aspects of health. It aids calcium absorption and is essential for maintaining healthy bones, immune function, and regulating mood. Research also suggests that there is a link low levels of vitamin D and low testosterone.
  • ZINC: Known for the role it plays in maintaining a healthy immune system, studies have also suggested that the mineral zinc is a promising ingredient for supporting testosterone production. [2]
  • VELVET BEAN: This shrub native to Asia is rich in the minerals potassium, magnesium, calcium, and iron, as well as phytonutrients and antioxidants. It has been studied for its potential in supporting cognitive function and mood because it contains an amino acid that plays an important role in supporting concentration, alertness, happiness, and memory. Studies also suggest that it may help men looking to support desire and healthy testosterone production. [11, 12]

Primal Total Male + by Primal Harvest[1]

Testosterone Support by Roman

Nugenix Total by Nugenix

Key Ingredients To Look For

Important Criteria

*We try to update product information as often as we can. Please visit product websites for more information.

Ingredients To Avoid

*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. 

Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Top5 Wellness has with our picks.

www.top5wellness.com

Bottom Line:

Primal Total Male by Primal Harvest features a blend of quality ingredients to help men looking to support their T-levels, muscle health, energy, mood, and general wellbeing. Expertly formulated for maximum potency, it delivers 50 mcg of vitamin D3, 150 mg of vitamin B3, 11 mg of zinc, and 110 mg of the mineral boron. It also contains superstar ingredients used in Ayurveda and TCM, including Korean red ginseng, fenugreek, maca root and shilajit extract, as well as antioxidant-supporting extracts, velvet bean, tribulus terrestris, and oat straw.*

This unique formula comes in easy-to-take capsules,  is independently third-party lab tested, and is manufactured in the USA with globally sourced ingredients. 

Another perk is that this men’s supplement offers great value for money and the company also has a convenient Subscribe & Save program which includes free shipping and a 20% discount. To top it off, every Primal Harvest product comes with a 90-day money-back guarantee

PROS

CONS

Our rating:

  • Contains vitamins D3, B3, and zinc
  • Formulated with a unique blend of plant extracts including tribulus terrestris, Korean ginseng, maca and more
  • With black pepper extract
  • Hormone-free
  • Easy-to-swallow, plant-based capsules
  • Certified safety and purity testing
  • 90-day money-back guarantee
  • Made in the USA with globally sourced ingredients
  • Only available online
  • Sometimes runs out of stock

How we rated the Top 5 Nutritional Supplements

Each of our reviews is based on a factual analysis and comparison. We examine the ingredients, dosages and manufacturing processes to understand the quality of the product. In addition, we evaluate customer reviews, value for money and customer service to protect our readers from negative buying experiences. Although we may receive compensation for these reviews, we strive to provide objective comparisons based on facts.

EFFECTIVENESS 

INGREDIENTS

PRICE-PERFORMANCE 

CUSTOMER SERVICE 

Top Supplements 2025

90-Day Money-Back Guarantee

Third Party Tested

Subscribe & Save Program

Bottom Line:

Testosterone Support by Roman is formulated with vitamin D3, zinc, magnesium, copper, maca root, and ashwagandha root. It features key ingredients such as vitamin D3, zinc, and maca and uses organic ashwagandha but contains fewer ingredients than some of the other products on this list. The 4-capsule serving size recommendation is a little larger than other products out there. You may also want to note that there is no information that is easily available confirming whether this product is third-party tested.

PROS

CONS

2. Testosterone Support

by Roman

Rating: B+

Our rating:

  • Contains vitamin D3, zinc, and magnesium
  • Formulated with maca root and ashwagandha
  • Hormone-free formula
  • 4-capsule per day serving size 
  • No third-party testing guarantee

Bottom Line:

Nugenix Total is a male support supplement formulated with zinc and B vitamins. Each bottle contains a month's supply of 90 capsules at 3 capsules per serving. However, you may want to note that it doesn’t contain some key nutrients like vitamin D. Additionally, the price is a bit steeper than some of the other products featured on this list. 

PROS

CONS

3. Nugenix Total

by Nugenix

Rating B

Our rating:

  • Contains zinc and B vitamins
  • Gluten-free
  • No vitamin D 
  • Capsules are not plant-based 
  • High price point

Bottom Line:

Testo Prime’s formula is a comprehensive approach to men’s wellness. This supplement features a range of ingredients including ashwagandha, green tea extract, zinc, vitamin D, B vitamins, and black pepper. However, at the time of writing this review, there were hardly any customer reviews online that haven’t been directly published by Testo Prime, so it may be hard to know a customer’s true experience. Also, there is no subscribe and save option, so you have to order in bulk if you want to stay consistent, which costs more money upfront. 

PROS

CONS

4. Testo Prime

by TestoPrime

Rating C+

Our rating:

  • Money back guarantee
  • Science-backed formula 
  • Features B vitamins, ashwagandha, and vitamin D
  • No subscription program 
  • Not many customer reviews

Our Choice 2025

  • Includes vitamin D and zinc
  • With vitamins, minerals, and herbal extracts
  • Third-party laboratory tested
  • Easy-to-swallow, plant-based capsules
  • USA made with globally sourced ingredients

Bottom Line:

Prime Test by Prime Labs is a testosterone support supplement featuring nettle leaf, saw palmetto extract, and wild yam extract. Although it is made in the US, some may want to note that this formula doesn’t include any vitamins or minerals and is only a herbal blend. It comes in caplet form with a serving size of 2 caplets per day. Finally, you may want to note that there is no mention of the product being third-party tested for quality available on the brand website.

PROS

CONS

5. Prime Test

by Prime Labs

Rating C

Our rating:

  • Contains T-Booster blend
  • Made in the US 
  • 2-caplet serving size
  • Lacks vitamin D and zinc 
  • Herbal blend only
  • No third-party testing guarantee

Citations

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Primal Harvest provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

1. “What You Need to Know about…Testosterone.” What You Need to Know About…Testosterone | News | UW Health, www.uwhealth.org/news/what-you-need-to-know-about-low-t. Accessed 11 May 2023. 

2. Fallah, Ali, et al. “Zinc Is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization.” Journal of Reproduction & Infertility, U.S. National Library of Medicine, 2018, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010824/.

3. Protich M;Tsvetkov D;Nalbanski B;Stanislavov R;Katsarova M; “[Clinical Trial of a Tribestan Preparation…].” Akusherstvo i Ginekologiia, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/6367515/.

4. Ștefănescu R;Tero-Vescan A;Negroiu A;Aurică E;Vari CE; “A Comprehensive Review of the Phytochemical, Pharmacological, and Toxicological Properties of Tribulus Terrestris L.” Biomolecules, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/32408715/.

5. RR;, Tambi MI;Imran MK;Henkel. “Standardised Water-Soluble Extract of Eurycoma Longifolia, [REDACTED]…?” Andrologia, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/21671978/.

6. Tambi, Mohd Ismail Bin Mohd, and M Kamarul Imran. “Eurycoma Longifolia Jack…” Asian Journal of Andrology, U.S. National Library of Medicine, May 2010, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739276/.

7. Talbott, Shawn M, et al. “Effect of [REDACTED] on Stress Hormones and Psychological Mood State in Moderately Stressed Subjects.” Journal of the International Society of Sports Nutrition, U.S. National Library of Medicine, 26 May 2013, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669033/.

8. Chen, Chee Keong, et al. “Effects of Eurycoma Longifolia Jack Supplementation Combined with Resistance Training on Isokinetic Muscular Strength and Power, Anaerobic Power, and Urinary Testosterone: Epitestosterone Ratio in Young Males.” International Journal of Preventive Medicine, U.S. National Library of Medicine, 5 July 2019, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639844/.

9. “Home - Books - NCBI.” National Center for Biotechnology Information, U.S. National Library of Medicine, https://www.ncbi.nlm.nih.gov/books.

10. Gonzales-Arimborgo C;Yupanqui I;Montero E;Alarcón-Yaquetto DE;Zevallos-Concha A;Caballero L;Gasco M;Zhao J;Khan IA;Gonzales GF; “Acceptability, Safety, and Efficacy of Oral Administration of Extracts of Black or Red Maca (Lepidium Meyenii) in Adult Human Subjects: A Randomized, Double-Blind, Placebo-Controlled Study.” Pharmaceuticals (Basel, Switzerland), U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/27548190/.

11. Tomita-Yokotani K;Hashimoto H;Fujii Y;Nakamura T;Yamashita M; “Distribution... in the Root of Velvet Bean Plant and Gravity.” Uchu Seibutsu Kagaku, U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/15858373/.

12. Maheshwari, Anuj, et al. “Efficacy of FurosapTm, a Novel Trigonella Foenum-Graecum Seed Extract, in Enhancing Testosterone Level and Improving Sperm Profile in Male Volunteers.” International Journal of Medical Sciences, U.S. National Library of Medicine, 10 Jan. 2017, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278660/.

14. M.Naghii, M. Mofid, A. Reza Asgari, M. Hedayati, M. Daneshpour, "Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines", U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/21129941.

15. T.Travison, J. Morley, A. Araujo, A. O'Donnell, J. McKinlay, "The relationship between libido and testosterone levels in aging men", U.S. National Library of Medicine, https://pubmed.ncbi.nlm.nih.gov/16670164/

Testosterone: Sex Hormone & Muscle Building

Muscle growth happens when resistance training places stress on muscle fibers, triggering muscle-protein synthesis to repair and strengthen them. Increased blood flow delivers nutrients, creating that "pump" effect.

However, many overlook the critical role of testosterone. This key hormone directly impacts muscle development, strength, and recovery. Low levels can slow progress, making it harder to build and maintain muscle mass. Supporting healthy testosterone levels through proper training, lifestyle choices, and supplementation can enhance results.

Testosterone contributes to maintaining muscle mass, bone density, fat metabolism, and sexual function, and is important for heart health, memory, mood, and brain function.*

Low testosterone may diminish drive, energy, and responsiveness, making time in the bedroom less satisfying. It can lead to fatigue, frustration, and difficulty maintaining excitement, causing emotional strain and embarassment.

Testo Prime by TestoPrime

Try To Avoid:

  • UNCLEAR LABELS: A quality men’s health supplement should clearly list exactly what’s included in the formula. Avoid products lacking transparency that don’t list all of the specific ingredients included in the formula.
  • MISSING SAFETY TESTING & CERTIFICATIONS: Choose a stress support supplement that has been independently third-party lab tested and manufactured in the USA. These precautions will guarantee that the product is top quality and free from unwanted extras, such as contaminants, traces of heavy metals, or pesticides.
  • FALSE OR MISLEADING CLAIMS: Beware of any supplements that claim their product treats or cures any specific disease or ailment, or promises miraculous, unrealistic, or misleading results. Always speak to your doctor before starting a new supplement routine.
  • SUSPICIOUSLY CHEAP PRODUCTS: When it comes to your physical health, this is definitely not an area to test out suspiciously cheap products. There are plentiful options to choose from that are high value and still affordable. In this case, you do get what you pay for!

Top 5 Testosterone Supplements Of 2025

Vitamin D

Zinc

Boron

Herbal Blend

Max. 3 Capsules

Plant-Based Capsule/Tablet

Not made in the USA

1. Primal Total Male +

by Primal Harvest[1]

Rating A+

Based on 3739 Reviews of Primal Harvest 

Primal Total Male+

by Primal Harvest[1]

What May Cause Low Testosterone?

There are several reasons why men begin to experience low testosterone levels, or T-levels. 

While the most common reason is that it’s a natural result of aging, lifestyle and other factors may also contribute to decreasing testosterone.*

Potential signs of low testosterone include…

  • Low energy*
  • Reduced drive *
  • Weight gain*
  • Muscle loss*
  • Increased body fat*
  • Hot flashes*
  • Fatigue*
  • Forgetfulness*

Note: Please seek professional medical advice if you think you are suffering from a hormone deficiency. These statements are not intended to diagnose, treat, cure, or prevent any disease or condition, nor are they intended to be substitutes for professional medical health advice. Always consult your physician or other qualified healthcare provider for accurate advice, diagnosis, and treatment plan.

  • Feeling down*
  • Moodiness/irritability*
  • Poor concentration*
  • Hair loss*
  • Bone concerns*

Some potential causes of low testosterone include:

  • Normal aging*
  • High body weight*

Note: These statements are not intended to diagnose, treat, cure, or prevent any disease or condition, nor are they intended to be substitutes for professional medical advice. Always consult your physician or other qualified healthcare provider for accurate advice, diagnosis, and treatment plan.

  • Emotional stress*
  • Physical stress *

Note: Supplements affect everyone differently and individual results may vary. 

How may other men's health supplements on the market not meet your needs?

Male supplements can get pretty complex. There are endless products to choose from, multiple different areas of men’s health, and the challenge of matching ingredients that safely complement one another.

All supplements for men are NOT created equal.

Unfortunately, some generic supplements for men or “testosterone boosters” may not meet your needs or expectations. Choosing the best possible formula all comes down to knowing what to look for and what try to avoid so that you never waste your time or hard-earned money. Here are the top things try to avoid when shopping for a men’s wellness support supplement:

Prime Test by Prime Labs

When it comes to physical intimacy, optimal testosterone levels play a critical role—you’re not just present, you’re primed for action. This key hormone enhances energy, confidence, and drive, making everything feel more natural and effortless. The difference is significant—when testosterone is at healthy levels, you feel stronger, more engaged, and consistently ready to take things to the next level. [15]