The Best Probiotics of 2025

Try To Avoid

Uncertain CFU count - CFUs, or colony-forming units, are a method of counting how much live bacteria is in a probiotic product. The amount of CFUs can vary from product to product and can change from 1 to 10 billion (though more is not always better).
Lack of Third-Party Testing - Always look for ‘third party lab-tested’ verifications that guarantee the product has been independently tested for any heavy metals, bacteria, pesticides, or traces of any other harmful substances. This helps to ensure safety and efficacy of the product.
Only One Strain - Some products contain a variety of probiotic strains to target different wellness needs.
Coated Improperly - Some are not enteric-coated (which means that it can travel through the digestive tract to get where it needs to for maximum benefits).*
Extremely Low or High Price - Do your research before buying an overpriced or suspiciously cheap supplement. Do not cut corners for your gut health.

Primal Biotics by Primal Harvest[1]

Ultimate Flora Probiotic by RenewLife

Probiotics

by Nature's Bounty

Raw Probiotics by Garden of Life

Key Ingredients To Look For

Important Criteria

*We try to update product information as often as we can. Please visit product websites for more information.

Ingredients To Avoid

*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

Trademarks utilized on our website belong to their respective owners and no implied or expressed endorsement of our website or services is intended. Rankings can be affected by the relationship Top5 Wellness has with our picks.

www.top5wellness.com

DO NOT SELL OR SHARE MY PERSONAL INFORMATION

Bottom Line:

Primal Probiotics are formulated with 31 billion CUFs from 12 dynamic probiotic strains, including L. acidophilus, L. rhamnosus, L. casei, B. longum, B. bifidum, and Bacillus coagulans. It combines these with Red Raspberry Seed and FOS (Fructo-Oligosaccaride) prebiotics.

Our team liked that the product comes in easy-to-swallow, once-daily capsules, making them convenient to add to a supplement routine.

The formula is third-party lab-tested and made in the USA. To top it off, they’re backed by a 90-day money-back guarantee.

Primal Probiotics’ pricing stands out, especially when you buy multiple bottles or sign up for their easy and convenient subscription service.

PROS

CONS

Our rating:

Contains 12 dynamic probiotic strains
With 31 billion CFUs
With Red Raspberry Seed and FOS Prebiotics
Made in the USA with globally sourced ingredients
90-day money-back guarantee
Third-party lab tested
Only one capsule a day

Only available online
Sometimes runs out of stock

How we rated the Top 5 Nutritional Supplements

Each of our reviews is based on a factual analysis and comparison. We examine the ingredients, dosages and manufacturing processes to understand the quality of the product. In addition, we evaluate customer reviews, value for money and customer service to protect our readers from negative buying experiences. Although we may receive compensation for these reviews, we strive to provide objective comparisons based on facts.

EFFECTIVENESS

INGREDIENTS

PRICE-PERFORMANCE

CUSTOMER SERVICE

Top Supplements 2025

90-Day Money-Back Guarantee

Third Party Tested

Subscribe & Save Program

Bottom Line:

This product is a great budget probiotic featuring a high CFU count from 12 diverse probiotic strains. It contains both Lacto and Bifido probiotic strains and is delivered in a once daily capsule. Unfortunately, you may note that it was missing some of the probiotic strains we were looking for as well as prebiotics. Although it had a 60-day money-back guarantee but still preferred products with a 90-day guarantee like our number one pick.

PROS

CONS

2. Ultimate Flora Probiotic

by RenewLife

Rating: B+

Our rating:

Over 20 billion CFUs
Made in the USA
12 diverse strains

No prebiotics
No L. reuteri, B. longum, or B. bifidum

Bottom Line:

Nature’s Bounty probiotics is a low-cost, GMP-certified supplement formulated to support digestive health with over 100 million active Lactobacillus acidophilus. This product comes in tablet form, which may be a downside for some since it’s generally thought that probiotics are better formulated in capsule form.

However, the main reason this product didn’t make it to the top was that it only contains one probiotic strain.

PROS

CONS

3. Probiotics

by Nature's Bounty

Rating C+

Our rating:

Contains L. acidophilus
GMP certified
1 tablet serving size

Only 1 probiotic strain
No Bifido strains

Bottom Line:

Digestive Daily Probiotic by Culturelle is a probiotic formula that includes 12 billion CFUs of the probiotic strain Lactobacillus rhamnosus GG.

You may note that they include the prebiotic inulin in the formula and that it comes in a one-capsule serving size.

However, the fact that this formula only contains one probiotic strain places it fourth on our list.

PROS

CONS

4. Digestive Daily Probiotic

by Culturelle

Rating C+

Our rating:

1 capsule serving size
Includes inulin (chicory root)

Only contains 1 probiotic strain
Only 12 billion CFUs
No Bifido strains

Our Choice 2025

USA-made with globally sourced ingredients
Potent Probiotic Strains For Men
FOS Prebiotics
Money Back Guarantee
Ultimate Synbiotic Supplement

Bottom Line:

Raw Probiotics by Garden of Life is a once-daily probiotic supplement that includes 100 billion CFUs of both Lacto and Bifido probiotic strains. This product includes a diverse selection of strains and has a high CFU count. While this product was relatively comparable to the other products on this list, the brand does not offer a 90-day money back guarantee which can be disappointing. Additionally, although that the formula includes a digestive blend, you may note that it did not include prebiotics and did contain milk.*

PROS

CONS

5. Raw Probiotics

by Garden of Life

Rating C

Our rating:

Once-daily capsule High CFU count and number
of probiotic strains
Includes enzymes blend

No 90-day money-back guarantee
No prebiotics
Contains milk

Citations

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Wellness Reviews provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

1. Integrative HMP (iHMP) Research Network Consortium. “The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles….” Cell host & microbe vol. 16,3 (2014): 276-89. doi:10.1016/j.chom.2014.08.014

2. Sender, Ron et al. “Revised Estimates for the Number of Human and Bacteria Cells in the Body.” PLoS biology vol. 14,8 e1002533. 19 Aug. 2016, doi:10.1371/journal.pbio.1002533

3. Durack, Juliana, and Susan V Lynch. “The gut microbiome…” The Journal of experimental medicine vol. 216,1 (2019): 20-40. doi:10.1084/jem.20180448

4. Al Bander, Zahraa et al. “The Gut Microbiota…: An Overview.” International journal of environmental research and public health vol. 17,20 7618. 19 Oct. 2020, doi:10.3390/ijerph17207618

To see a list of our other references, please click here.

Who Might Benefit From A Probiotic?*

Wants to maintain regularity*

Finds it hard to consume probiotics through food*

Occasionally experiences digestive issues*

What Is A Probiotic?

Probiotics are live bacteria and yeast that live in your gut microbiome.

Whenever you see the term “gut microbiome,” it’s referring to all of the microorganisms living within your gut. Some of them may be potentially harmful, so-called “bad” bacteria. On the other hand, some are thought to be beneficial, often called “good” or “friendly” bacteria, aka probiotics. [1, 2, 3, 4]

Researchers believe that having optimal gut health typically means having a good balance between the “bad” bacteria and the “good" bacteria. Ideally, they should co-exist peacefully within the gut.[1, 2, 3, 4]

Everyone’s needs are different, but some people who may benefit from taking a probiotic supplement include anyone who:

Sometimes has a difficult time passing stool*

Feels bloated or constipated occasionally*

Adding a probiotic to your routine may help support:

Potential Benefits of Taking Probiotics*

Digestion*
Overall Gut Health*
Occasional Bloat*
Immune Health*
Occasional Constipation and Excess Gas*

Note: Individual results may vary. The benefits stated are based on personal experiences and subjective feedback and may vary from person to person.

Look For:

Contains high quality probiotic strains
Includes prebiotics
1 capsule serving size
Fair price
Great customer service and return policy
Made in USA
Third-party laboratory tested

Digestive Daily Probiotic by Culturelle

Probiotics can be found in some fermented foods like yogurt, kefir, kimchi, sauerkraut, and miso. They are also available as dietary supplements. This may be more convenient for some people to consume, especially if they struggle to eat enough probiotic-rich foods.

Occasionally feels run-down or sluggish*

Wants better skin health*

Note: These statements are not intended to diagnose, treat, cure, or prevent any disease or condition, nor are they intended to be substitutes for professional medical health advice. Always consult your physician or other qualified healthcare provider for accurate advice, diagnosis, and treatment plan.

Comfortable Regularity*
Healthy Weight Management*
Energy*
Healthy skin*

Everyone has individual needs and the experience of making changes in your wellness routine will vary from person to person. Here are some examples of how including more daily probiotic support may look for different people:

How might you benefit from a probiotic supplement?^*

Noticing that their digestion felt smooth*
Experiencing consistency in regular bowel movements*
Seeing visible changes in their skin health*

How might you benefit from a adding an electrolyte powder to your routine?*

1 – 2 Months

6 + Months

Feeling good about their gut*
Finding that they had an easy time with weight management*
Generally feeling light*
Feeling satisfied with their regularity and digestion*

3 – 6 Months

Noticing digestive comfort*
Bloat support*
Feeling full for long*

Note: Individual results may vary. The benefits stated are based on personal experiences and subjective feedback and may vary from person to person.

Try To Avoid:

Choosing based on price
Not checking the label
Inconvenient serving size
Lack of clarity on the type of strain
Unstated CFU numbers
Supplements with only one probiotic strain

Top Probiotic Supplements Of 2025

Over 20 billion CFUs

12 Strains

Lactobacillus acidophilus

Lactobacillus rhamnosus

Lactobacillus reuteri

Lactobacillus casei

Bifidobacterium longum

Bifidobacterium lactis

Bifidobacterium bifidum

Prebiotics

No Soy

No Dairy

Not Only One Probiotic Strain

1. Primal Biotics

by Primal Harvest[1]

Rating A+

Based on 3739 Reviews of Primal Harvest

Primal Biotics

by Primal Harvest[1]