The Best Probiotics for Vaginal Health in 2025

Look For

Primal Probiotics by Primal Harvest[1]

Happy Hoo-Ha by OLLY

Once Daily Women’s by Garden Of Life

URO Probiotic by OPositiv

Good To Have

Important Criteria

*We try to update product information as often as we can. Please visit product websites for more information.

Try To Avoid

*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Bottom Line:

Primal Probiotics by Primal Harvest delivers 31 billion CFUs from 12 diverse probiotic strains, plus Red Raspberry Seed and FOS prebiotics for enhanced support. The once-daily, delayed-release capsules are easy to take and help ensure the probiotics reach where they’re needed. It’s third-party tested, made in the USA, and was the only product on this list backed by a 90-day money-back guarantee.

PROS

CONS

Our rating:

Contains 12 dynamic probiotic strains
With 31 billion CFUs
With Red Raspberry Seed and FOS Prebiotics
Made in the USA with globally sourced ingredients
90-day money-back guarantee
Third-party lab tested
Convenient once-daily capsule

Only available online
Sometimes runs out of stock

How we rated our Top 5 Probiotics

Each of our reviews is based on a factual analysis and comparison. We examine the ingredients, dosages and manufacturing processes to understand the quality of the product. In addition, we evaluate customer reviews, value for money and customer service to protect our readers from negative buying experiences. Although we may receive compensation for these reviews, we strive to provide objective comparisons based on facts.

EFFECTIVENESS

INGREDIENTS

PRICE-PERFORMANCE

CUSTOMER SERVICE

Top Probiotics for Vaginal Health in 2025

90-Day Money-Back Guarantee

Third-Party Tested

Subscribe & Save Program

Bottom Line:

Happy Hoo-Ha by OLLY includes 2 Lactobacillus strains: Lactobacillus acidophilus La-14 and Lactobacillus rhamnosus HN001. It’s also free from artificial additives, gluten, and sugar.

However, their ‘Vaginal Probiotic Blend’ contains just 10 billion CFUs of probiotics. The formula also doesn’t include prebiotics, which could impact its overall efficacy.

PROS

CONS

2. Happy Hoo-Ha

by OLLY

Rating: B+

Our rating:

Includes Lactobacillus acidophilus La-14 and Lactobacillus rhamnosus HN001
No artificial additives

No prebiotics
Under 20 billion CFUs (10 billion per serving)

Bottom Line:

This probiotic features a blend of Lactobacillus and Bifidobacterium cultures, plus an organic prebiotic fiber blend for added support. It's a solid choice for women looking for a supplement with good probiotic diversity.

Unlike our top pick, it lacks delayed-release capsules, which may affect how many probiotics survive digestion and stomach acid to deliver effective results. The return policy is also limited to 60 days.

PROS

CONS

3. Once Daily Women’s

by Garden Of Life

Rating B

Our rating:

Includes Lactobacillus and Bifidobacterium strains
Organic prebiotic fiber blend

No delayed-release capsules
Shorter return window (60 days)

Bottom Line:

Women’s Care Probiotic by RenewLife includes a range of Lactobacillus and Bifidobacterium strains to support digestive and feminine health. The once-daily capsule makes it convenient to incorporate into a daily routine.

However, the formula doesn’t include any prebiotics for additional support, and once again, the money-back guarantee is limited to 60 days.

PROS

CONS

4. Women’s Care Probiotic

by RenewLife

Rating C+

Our rating:

Includes diverse Lactobacillus and Bifidobacterium strains
Convenient once-daily capsule

No prebiotics
Shorter return window (60 days)

Our Choice 2025

Supports vaginal microbiome and feminine wellness*
12 dynamic probiotic strains
31 billion CFUs probiotics
Includes prebiotics to help nourish good bacteria.*
Made in the USA with globally sourced ingredients
90-day money-back guarantee

Bottom Line:

URO Probiotic by OPositiv includes a Lactobacillus blend and XOS prebiotics, which can help nourish good bacteria. It’s a straightforward formula with a clean label and simple ingredient profile.

That said, it delivers just 5 billion CFUs and relies primarily on a single strain group - Bifidobacterium, which may limit its overall diversity and potential impact.

PROS

CONS

5. URO Probiotic

by OPositiv

Rating C

Our rating:

Includes XOS prebiotics
Lactobacillus probiotic blend

Low CFU count (5 billion per serving)
Single strain group (Bifidobacterium only)

Citations

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Wellness Reviews provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

1. Integrative HMP (iHMP) Research Network Consortium. “The Integrative Human Microbiome Project: dynamic analysis of microbiome-host omics profiles….” Cell host & microbe vol. 16,3 (2014): 276-89. doi:10.1016/j.chom.2014.08.014

2. Sender, Ron et al. “Revised Estimates for the Number of Human and Bacteria Cells in the Body.” PLoS biology vol. 14,8 e1002533. 19 Aug. 2016, doi:10.1371/journal.pbio.1002533

3. Durack, Juliana, and Susan V Lynch. “The gut microbiome…” The Journal of experimental medicine vol. 216,1 (2019): 20-40. doi:10.1084/jem.20180448

4. Al Bander, Zahraa et al. “The Gut Microbiota…: An Overview.” International journal of environmental research and public health vol. 17,20 7618. 19 Oct. 2020, doi:10.3390/ijerph17207618

To see a list of our other references, please click here.

How probiotics support vaginal health

Is Your Vaginal Microbiome Out of Balance?

Even with the best hygiene and habits, your vaginal flora can shift. Here are some signs that your vaginal microbiome may be unbalanced.

A lingering, unpleasant odor
Unusual discharge
Itching, dryness, or irritation
Feeling ‘off’ around your cycle or after intimacy
A general sense of unease or discomfort

Your vaginal microbiome relies on Lactobacillus bacteria to maintain a healthy pH and create an environment that’s less welcoming to unwanted bacteria and yeast. Things like stress, antibiotics, or hormonal changes can throw that balance off. Probiotics help restore it.

Strains like Lactobacillus rhamnosus, acidophilus, reuteri, and gasseri can be especially effective at supporting vaginal health. They help maintain pH, reinforce your natural defenses, and promote long-term balance.

Top formulas also include FOS, a prebiotic that feeds good bacteria, and delayed-release capsules to help probiotics survive digestion and reach the vaginal tract where they’re most effective.

Everyone’s needs are different, but probiotic supplements may be a great fit for women who:

Is a probiotic suitable for you?

Want consistent support for vaginal balance and comfort*
Deal with consistent unpleasant vaginal odor.*

Note: These statements are not intended to diagnose, treat, cure, or prevent any disease or condition. They are based on personal experiences and subjective feedback. Always consult your healthcare provider for individual guidance.

Multi-strain formulas (10+ strains)

More strains provide broader support for a balanced microbiome.

High CFU counts of key strains (L. reuteri, L. gasseri, L. casei)

These strains are essential for maintaining vaginal pH balance and overall health.

Lactobacillus and Bifidobacterium species

These strains help promote a healthy vaginal environment by supporting beneficial bacteria.

Prebiotics like FOS

Prebiotics fuel probiotics, enhancing their effectiveness and survival.

Women’s Care Probiotic by RenewLife

Your vaginal microbiome is very senstive, and can be negatively influenced by factors such as:

Hormonal fluctuations
Stress
Sexual activity
Antibiotics
Lifestyle choices (such as smoking or douching)

Experience occasional irritation, discharge, or imbalance*
Are looking for a daily probiotic that supports both vaginal and digestive health*

While everyone’s experience is unique, here’s how consistent use of a high-quality probiotic may look over time:

Smoother digestion and less bloating*
Feeling fresher throughout the day*
Fewer cravings for sugar or simple carbs*

How might probiotics benefit your vaginal health?

SHORT TERM

LONG TERM

Ongoing support for vaginal and gut health*
Feeling lighter, more comfortable, and more satisfied overall*

MID TERM

Improved vaginal comfort*
Clearer-looking skin*
More regular digestion and elimination*

Note: Individual results may vary. These benefits are based on personal experiences and subjective feedback and may not apply to everyone.

Try To Avoid:

Top Probiotics for Vaginal Health in 2025

20+ Billion CFUs

Lactobacillus Strains

Bifidobacterium Strains

Prebiotics

Delayed Release Capsules

Artificial Additives

Low CFU counts (under 20 billion)

Single-Strain Formula

1. Primal Probiotics

by Primal Harvest[1]

Rating A+

Based on 3739 Reviews of Primal Harvest

Primal Probiotics

Our top-rated probiotics to support a balanced vaginal microbiome.

What to look for (and what to avoid) in probiotics

Here’s what to look for and what to avoid when choosing a probiotic for vaginal wellness:

Delayed-release capsules

Protects probiotics from stomach acid, ensuring they reach the vaginal tract intact.

Botanical ingredients (e.g., Red Raspberry Seed)

Natural plant-based ingredients can provide additional support for reproductive health.

Clean, transparent labels

Look for products free from artificial additives, fillers, and allergens.

Single-strain formulas

Lack of strain diversity limits effectiveness and doesn’t support a well-rounded microbiome.

Low CFU counts

Insufficient colony-forming units may not provide noticeable results or support long-term balance.

Lack of prebiotics

Without prebiotics, probiotics may not survive long enough to offer full benefits.

Artificial additives, fillers, or sweeteners

These unnecessary ingredients may compromise the purity and effectiveness of the probiotic.

Unclear or incomplete ingredient lists

Avoid products with vague or incomplete labels that don’t clearly show what’s inside.

by Primal Harvest[1]